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• 20/12/2008  -  Combined radiation and hormonal therapy or dose escalation for men with unfavourable-risk prostate cancer: an evidence-based approach using a synthesis of randomized clinical trials
  There continues to be a significant number of men who initially present with localized but unfavourable disease, with resulting morbidity and mortality. Clinicians need to optimize their therapeutic strategies for these men.
• 19/12/2008  -  A critical analysis of the role of gut Oxalobacter formigenes in oxalate stone diseaseA critical analysis of the role of gut Oxalobacter formigenes in oxalate stone disease
  The gut-dwelling obligate anaerobe Oxalobacter formigenes (OF) has attracted attention for its oxalate-degrading property. In this review we critically evaluate published studies and identify major gaps in knowledge.
• 26/08/2008  -  Phosphodiesterase type 5 inhibitors in the management of erectile dysfunction secondary to treatments for prostate cancer: findings from a Cochrane systematic review
  BridgetCandy, Louise Jones, Rachael Williams, Adrian Tookman and Michael King
• 19/05/2008  -  The modern management of upper tract urothelial cancer: surgical treatment
  Mario Fernández Arancibia, Christian Bolenz, Maurice-Stephan Michel, Francis X. Keeley Jr, Peter Alken
• 19/05/2008  -  Present strategies in the treatment of metastatic renal cell carcinoma: an update on molecular targeting agents
  Joaquim Bellmunt, Clara Montagut, Santiago Albiol, Joan Carles, Pablo Maroto, Anna Orsola
• 19/05/2008  -  Radical prostatectomy with positive surgical margins: how are patients managed?
  RAMESH THURAIRAJA, JONATHAN OSBORN, JONATHAN MCFARLANE, AMIT BAHL, RAJENDRA PERSAD
• 16/05/2008  -  The pharmacological treatment of premature ejaculation
  Premature ejaculation (PE) is a common sexual dysfunction in men that is characterized by a short time to ejaculation, and a lack of control over ejaculation, and is associated with distress for men and their partners. Lack of knowledge about the aetiology of PE and lack of approved treatments might contribute to its under-diagnosis and under-treatment.
• 05/05/2008  -  The role of botulinum toxin in BPH
  Currently there is growing interest in finding new therapies for BPH. One novel technique is intraprostatic injection with botulinum toxin type-A (BTX-A). While its mechanism of action is not entirely understood, recent studies have suggested that it might be effective for symptomatic disease.
• 13/04/2008  -  Is the use of parasympathomimetics for treating an underactive bladder evidence based?
  An underactive urinary bladder (UUB), often occurring after surgery, can lead to urinaryretention even in otherwise healthy people. We systematically reviewed publishedreports to determine whether the use of parasympathomimetic agents is warranted inpatients with a UUB.
• 13/04/2008  -  The urologist’s guide to low dose-rate interstitial brachytherapy with permanent seed implants for localized prostate cancer
  The use of interstitial brachytherapy with permanent seed implantation for localizedprostate cancer has rapidly gained popularity during the past decade; about a third ofpatients submitted for radiotherapy are now treated with this method in the USA.
• 09/04/2008  -  A population-based study of urinary symptoms and incontinence: the Canadian Urinary Bladder Survey
  To ascertain the prevalence of lower urinary tract symptoms (LUTS) and urinary incontinence (UI) in Canada, using a cross-Canada telephone survey, as there is a wide discrepancy in the reported prevalence of these conditions.
• 07/02/2008  -  Complementary and alternative medicine in urology
  An increasing interest in, and use of, complementary and alternative medicine (CAM) is widely documented for the management of numerous diseases, to relieve symptoms in various conditions and to improve general health and well-being, even in Western countries.
• 07/02/2008  -  The three As of chronic prostatitis therapy: antibiotics, alpha-blockers and anti-inflammatories. What is the evidence?
  The three most common medications prescribed by physicians for treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) include antibiotics, α-blockers and anti-inflammatories. Until recently there has been no conclusive evidence to judge their efficacy in ameliorating CP/CPPS symptoms in clinical practice.
• 07/02/2008  -  Interstitial cystitis: a review of immunological aspects of the aetiology and pathogenesis, with a hypothesis
  Inflammation of the bladder is a common disease mainly affecting women. Patients may complain of suprapubic pain, urinary frequency and urgency with or without haematuria on repeated occasions.
• 07/02/2008  -  The pharmacological treatment of urinary incontinence
  The bladder and urethra constitute a functional unit which is controlled by a complex interplay between the central and peripheral nervous systems and local regulatory factors. Malfunction at various levels may result in micturition disorders, which roughly can be classified as disturbances of storage or of emptying.
• 07/02/2008  -  Assessment of sexual dysfunction in patients with benign prostatic hyperplasia
  Sexual dysfunction is a highly prevalent condition in ageing men that considerably affects their quality of life (QoL), although it is a frequently neglected aspect of healthcare.
• 07/02/2008  -  Impact of medical treatments for benign prostatic hyperplasia on sexual function
  LUTS and sexual dysfunction are highly prevalent in ageing men.
• 07/02/2008  -  Combination of phosphodiesterase-5 inhibitors and -blockers in patients with benign prostatic hyperplasia: treatments of lower urinary tract symptoms, erectile dysfunction, or both?
  Risk factors for BPH/LUTS and erectile dysfunction (ED) are well known; they include increasing age, weight gain and abdominal adiposity in adulthood, smoking (nicotine increases sympathetic activity), and excessive alcohol intake (>75 g/day).
• 07/02/2008  -  Neurophysiology of the ejaculatory process: developing perspectives
  From a classical standpoint, sexual behaviour/activity in men presupposes many dimensions or phases, including the presence of libido or sexual interest, sexual arousal, ejaculation, and orgasm.
• 07/02/2008  -  Ejaculatory disorders and sexual function
  Recent advances in the knowledge and treatment of erectile dysfunction have increased patient and practitioner awareness of other sexual problems, particularly ejaculatory disorders (EjD).

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